CORRELATION OF HbA1c AND TG/ HDL RATIO IN PROLANIS TYPE 2 DIABETES MELLITUS PATIENTS

Abstract

Background: Diabetes mellitus (DM) is a chronic metabolic disease characterized by insulin deficiency and prolonged hyperglycemia, that leads into an interferences in metabolic processes in the body. HbA1c is the gold standard for glycemic control, reflecting the average blood glucose levels in patients over approximately three months. Type 2 DM (T2DM) patients with low HbA1c levels have a triglyceride-to-HDL (TG/HDL) ratio that is roughly 3 to 4 times lower compared to patients with higher HbA1c levels. Object: This study aims to determine the correlation between HbA1c levels and the TG/HDL ratio in patients with T2DM who participating in the Prolanis program. Method: The study employed a cross-sectional observational design based on primary data collected from December 2023 to April 2024, with a total sample of 50 T2DM patients in the Prolanis group at the primary health facility in Bangkalan Regency. The examinations were carried out at Farmalab. HbA1c was measured using the Wondfo FIA meter plus FS 113, while triglycerides (TG) and HDL cholesterol were analyzed using a Microlab 300 photometer. Data were analyzed using the Spearman correlation test. Result: The results showed that 100% of T2DM patients in the Prolanis group had HbA1c levels above normal values. Among these, 40% had TG/HDL ratios above normal values, 32% had normal TG/HDL ratios, and 28% had TG/HDL ratios below normal values. Based on the Spearman correlation test, the results obtained p = 0,043 (< 0,05). Conclusion: There is a correlation between HbA1c levels and the ratio of TG/HDL in T2DM patients in the Prolanis Group.